4 ms·

Antimicrobial resistance now a leading cause of death worldwide, study finds

34 points by nimbius 5y ago

fatboy93 5y ago
I'm not sure why this line of research is not being done more to be really honest. We are in Dire need of new antibiotics and updated books/documentation/procedures that don't use antibiotics willy nilly. I'm saying this as a biologist and a bioinformatician. Hyper-effective antibiotics like Linezolids and Vancomycin are really one of the last bastions of safety. And hospitals are probably one of the easiest ways to spread R-Strains (resistant strains). My infant who just a month and a half old was admitted back to the hospital after he stopped moving his right shoulder. We just got discharged a few days back. Pus, blood cultures and tens of tests later we found it was MRSA, or Methicillin resistant staph aureus. We narrowly escaped complete sepsis after multiple invasive drainage procedures and being constantly monitored in Nicu with multiple antibiotics. Pretty sure that it was a hospital infection considering the incubation period of the bacteria is around 10-14 days and we were back admitted at his 14th day of life. Antibiotic resistance is also a big issue with cattle and lifestock, along with effluence in the drainage near pharma industries as well. I rue the day that we cease finding effective antibiotics, because hell will break loose definitely then.
- netizen-936824 5y ago
  Can you recommend a good protein target to drug or reading material on possible targets? I'm not very familiar with this particular field of pharmacology
questiondev 5y ago
this and the amount of additives we have in our food supply here in the us. many of the color additives have been studied and many are considered immunosuppressants and abundantly found in many many many foods that you wouldn’t even think of, check out the app yuka, it allows you to scan upc codes and it will give you a readout of all the studies on each additive a product has and whether it has any adverse affects. many hazardous additives are allowed to be used in our food supply.
nate_meurer 5y ago
From the article: > "More than 1.2 million – and potentially millions more – died in 2019 as a direct result of antibiotic-resistant bacterial infections, according to the most comprehensive estimate to date of the global impact of antimicrobial resistance (AMR)." > "The analysis shows AMR was directly responsible for an estimated 1.27 million deaths worldwide, and associated with an estimated 4.95 million deaths, in 2019." So, roughly a COVID-epidemic's worth of people are dying each year directly from these bacterial infections, and multiples more from complications. And the death rate is accelerating.

34 points by nimbius 5y ago

I'm not sure why this line of research is not being done more to be really honest. We are in Dire need of new antibiotics and updated books/documentation/procedures that don't use antibiotics willy nilly. I'm saying this as a biologist and a bioinformatician. Hyper-effective antibiotics like Linezolids and Vancomycin are really one of the last bastions of safety. And hospitals are probably one of the easiest ways to spread R-Strains (resistant strains). My infant who just a month and a half old was admitted back to the hospital after he stopped moving his right shoulder. We just got discharged a few days back. Pus, blood cultures and tens of tests later we found it was MRSA, or Methicillin resistant staph aureus. We narrowly escaped complete sepsis after multiple invasive drainage procedures and being constantly monitored in Nicu with multiple antibiotics. Pretty sure that it was a hospital infection considering the incubation period of the bacteria is around 10-14 days and we were back admitted at his 14th day of life. Antibiotic resistance is also a big issue with cattle and lifestock, along with effluence in the drainage near pharma industries as well. I rue the day that we cease finding effective antibiotics, because hell will break loose definitely then.

netizen-936824 5y ago
Can you recommend a good protein target to drug or reading material on possible targets? I'm not very familiar with this particular field of pharmacology

questiondev 5y ago

this and the amount of additives we have in our food supply here in the us. many of the color additives have been studied and many are considered immunosuppressants and abundantly found in many many many foods that you wouldn’t even think of, check out the app yuka, it allows you to scan upc codes and it will give you a readout of all the studies on each additive a product has and whether it has any adverse affects. many hazardous additives are allowed to be used in our food supply.

nate_meurer 5y ago

From the article: > "More than 1.2 million – and potentially millions more – died in 2019 as a direct result of antibiotic-resistant bacterial infections, according to the most comprehensive estimate to date of the global impact of antimicrobial resistance (AMR)." > "The analysis shows AMR was directly responsible for an estimated 1.27 million deaths worldwide, and associated with an estimated 4.95 million deaths, in 2019." So, roughly a COVID-epidemic's worth of people are dying each year directly from these bacterial infections, and multiples more from complications. And the death rate is accelerating.