The first issue I've seen people struggle with are to do with generating the Python bindings in the right modules. Getting the right combination of arguments to

The first issue I've seen people struggle with are to do with generating the Python bindings in the right modules. Getting the right combination of arguments to protoc isn't always obvious. The main complexity with an existing code base is that gRPC runs its own ioloop so it controls the server entirely so you can't glue it into an existing Python webapp easily. You can call all your existing Python functions etc just fine though.