to really attempt a simulation at it you'd need to build something along the same general concept as biosphere-2 (but much bigger, with more supplies, more redu

to really attempt a simulation at it you'd need to build something along the same general concept as biosphere-2 (but much bigger, with more supplies, more redundancy, higher budget etc) and then put it at the very far end of an extremely difficult and arduous logistics chain for periodic resupply.