3 ms·
Genomes are sequenced when they're both accessible and are of scientific/economic interest. This results in an overrepresentation of: - Humans and their pathog
by etaoins 5y ago
Genomes are sequenced when they're both accessible and are of scientific/economic interest. This results in an overrepresentation of:
- Humans and their pathogens
- Economically important organisms (e.g. crops and farm animals) and their pathogens
- Model organisms
For example, compare the number of Genebank sequences for HIV-1 [1] versus Feline immunodeficiency virus [2]. HIV-1 is additionally problematic because it has an extremely high mutation rate [3], making it more likely for a random sequence to match some sequenced HIV-1 genome.
[1]: https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Tree&id=11676&lvl=3&lin=f&keep=1&srchmode=1&unlock https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mod...
[2]: https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Tree&id=11673&lvl=3&lin=f&keep=1&srchmode=1&unlock https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mod...
[3]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574155/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574155/