6 ms·
More about her. "Also, Dr. Shi was trained by Ralph S. Baric of the University of North Carolina in building “chimera” viruses — taking, for example, the spike
by basch 5y ago
More about her.
"Also, Dr. Shi was trained by Ralph S. Baric of the University of North Carolina in building “chimera” viruses — taking, for example, the spike protein from a new virus and splicing it to the backbone of a known one like SARS. He invented “no-see-um” techniques that left no trace of the splice."
source https://donaldgmcneiljr1954.medium.com/how-i-learned-to-stop-worrying-and-love-the-lab-leak-theory-f4f88446b04d https://donaldgmcneiljr1954.medium.com/how-i-learned-to-stop...
https://www.researchgate.net/publication/8119695_Development_of_mouse_hepatitis_virus_and_SARS-CoV_infectious_cDNA_constructs https://www.researchgate.net/publication/8119695_Development...
- akiselev 5y ago> the spike protein from a new virus and splicing it to the backbone of a known one like SARS The spike protein was already a defining feature of SARS-CoV when it emerged and became "known" [1]. That's why it was classified as a coronavirus! [2] Edit: Appears I have misread, see reply [1] https://www.science.org/doi/abs/10.1126/science.1086418 https://www.science.org/doi/abs/10.1126/science.1086418 [2] https://en.wikipedia.org/wiki/Coronavirus#Structure https://en.wikipedia.org/wiki/Coronavirus#Structure
- basch 5y agoI dont fully follow what you are saying. The statement was about grafting a new spike in place of an old one. Where is it implied that SARS doesnt have a spike? I dont even think that is the important takeaway. The no-see-um editing technique can apply to more than just spike proteins. I dont think its being implied that thats what happened.