I think the biggest difference is just that the layout algorithm for the DOM is a lot more complex than those for native apps. Changing one element might reflow

I think the biggest difference is just that the layout algorithm for the DOM is a lot more complex than those for native apps. Changing one element might reflow the whole page. Native frameworks aren't like that, and the solution they're converging on is the one React pioneered for the web, which is making a control's data dependencies explicit so you know when it needs to be updated.