2 ms·

I've always been a little fuzzy on this and would love for someone else to chime in. It's my understanding that raw marijuana contains both psychoactive cannab

by radlad 5y ago

I've always been a little fuzzy on this and would love for someone else to chime in. It's my understanding that raw marijuana contains both psychoactive cannabinoids as well as precursors which require decarboxylation. If that's the case, I am not sure that decarboxylation is _required_ - however it is recommended as it increases the _amount_ of bioavailable cannabinoids (i.e. best bang for your buck.)

hunterb123 5y ago
It's unlikely for cannabinoids other than THC to bind to the CB1 receptor strong enough to cause the psychoactive effect. Only THC binds very well to the CB1 receptor. THCA does not bind well to either receptor. Cannabinoids that bind to CB2 receptors in the immune and gastrointestinal systems affect inflammatory and immune responses.