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We have no proof that civets gave us SARS-1 and not the other way around. Since it was also found in raccoon dogs, ferret badgers and domestic cats which one o
by lamontcg 5y ago
We have no proof that civets gave us SARS-1 and not the other way around.
Since it was also found in raccoon dogs, ferret badgers and domestic cats which one of those was the actual intermediate animal? Civets were just the first identified. Either one of them gave it to us and we gave it to the other three, or possibly we got it from bats and gave it to all four. AFAIK there's no conclusive phylogenetic analysis establishing which species got it from whom.
MERS is much more obvious what happened.
- tripletao 5y agoI think you're strictly right there. If they'd obtained sequences then they could have built that tree; but as far as I know they didn't, perhaps because the cost of sequencing was higher back then. That's still more evidence than we have for SARS-CoV-2, though. With SARS-1 we had the additional evidence that some wildlife traders had antibodies, presumably from mild infections by related viruses in the animals they handled. There's again no genomic evidence to exclude "reverse zoonosis" there, but the timing seems to make that pretty unlikely. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140695/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140695/