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Another major difference between SARS-CoV and SARS-CoV-2 is that SARS-CoV-1 took time to gain new adaptions to effectively spread between humans. These mutation
by baja_blast 5y ago
Another major difference between SARS-CoV and SARS-CoV-2 is that SARS-CoV-1 took time to gain new adaptions to effectively spread between humans. These mutations that SARS-CoV-1 went through allowed researchers to find the intermediate animal host within months.
With SARS-CoV-2 there was no known mutation phase where the virus rapidly gained mutations to more efficiently transmit between humans. SARS-COV2 came out the gate perfectly adapted and did not start mutating extensively until many months after it spread globally. These lack of adaptations are also the reason why it's so hard to trace back to the original intermediate host species.
- jacquesm 5y ago> SARS-COV2 came out the gate perfectly adapted We actually do not know this for sure. There is a chance that the reservoir is one step removed and that another host in between amplified the virus to the point where it could make the jump. Ebola also has this property, but it is just a bit too lethal to spread far (fortunately). An Ebola with a slightly longer asymptomatic incubation time (while already shedding) would be far worse then the current versions. With Ebola each and every outbreak starts with an interspecies jump, usually bushmeat. The idea that these jumps are extremely rare is in principle incorrect, but it looks like that because pandemics are rare. But those are just the runaway successes (from the viral point of view).