You don't need to hook it up the brain. Transplanted hearts are generally not innervated. https://academic.oup.com/eurheartj/article/39/20/1799/2900507 https:/

You don't need to hook it up the brain. Transplanted hearts are generally not innervated. https://academic.oup.com/eurheartj/article/39/20/1799/2900507 https://academic.oup.com/eurheartj/article/39/20/1799/290050... As a result, they do not correctly respond to higher demand by beating faster, but this is a deficiency that is considered acceptable. Heart transplant recipients aren't routinely running marathons.