3 ms·

It seems like those are not quite there yet: How to Build an Artificial Heart https://www.newyorker.com/magazine/2021/03/08/how-to-build-an-artificial-heart htt

by mhb 5y ago

It seems like those are not quite there yet: How to Build an Artificial Heart https://www.newyorker.com/magazine/2021/03/08/how-to-build-an-artificial-heart https://www.newyorker.com/magazine/2021/03/08/how-to-build-a...

josephcsible 5y ago
A bunch of people do have artificial hearts. I'm wondering what about this patient made one not suitable for him.
- bogwog 5y ago
  Maybe cost? Those things ain't cheap.
iancmceachern 5y ago
Yes they are. The syncardia TAH, Heartmate 2 and 3, Carmet, etc.
- s1artibartfast 5y ago
  All with severe limitations
  - iancmceachern 5y ago
    Not really. Patients are able to leave the hospital, go home and resume normal life. They need to charge and maintain batteries on their person, and maintain the driveline exit site but all in all they have less limitations than say someone on dialysis.
    - s1artibartfast 5y ago
      Of course current LVADs are better than being dead, but still significantly worse than having a healthy heart, or transplant. Heartmate III is one of the best and here are some summary outcomes[1]: 2 year survival after LVAD implant is around ~75% 2 year chance of stroke is ~10% 2 year chance of major infection is 58%, and sepsis is 15% 2 year chance of right heart failure is 34%. Quality of life post implant and depression are real concerns. Some smaller studies have shown 5 year suicide rates as high as 10% following LVAD implantation. Don't get me wrong, they are a miracle of modern science and engineering, but have limitations. There are reasons why they are not a destination therapy for people eligible to receive transplants. https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejhf.2211 https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejhf.2211
      - iancmceachern 5y ago
        Indeed, well said. It's important to also note that 2 year survival rates after a heart transplant are similar, 75%-80% survival 2 years after a heart transplant.

by mhb 5y ago

josephcsible 5y ago

A bunch of people do have artificial hearts. I'm wondering what about this patient made one not suitable for him.

bogwog 5y ago
Maybe cost? Those things ain't cheap.

iancmceachern 5y ago

Yes they are. The syncardia TAH, Heartmate 2 and 3, Carmet, etc.

s1artibartfast 5y ago
All with severe limitations
- iancmceachern 5y ago
  Not really. Patients are able to leave the hospital, go home and resume normal life. They need to charge and maintain batteries on their person, and maintain the driveline exit site but all in all they have less limitations than say someone on dialysis.
  - s1artibartfast 5y ago
    Of course current LVADs are better than being dead, but still significantly worse than having a healthy heart, or transplant. Heartmate III is one of the best and here are some summary outcomes[1]: 2 year survival after LVAD implant is around ~75% 2 year chance of stroke is ~10% 2 year chance of major infection is 58%, and sepsis is 15% 2 year chance of right heart failure is 34%. Quality of life post implant and depression are real concerns. Some smaller studies have shown 5 year suicide rates as high as 10% following LVAD implantation. Don't get me wrong, they are a miracle of modern science and engineering, but have limitations. There are reasons why they are not a destination therapy for people eligible to receive transplants. https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejhf.2211 https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejhf.2211
    - iancmceachern 5y ago
      Indeed, well said. It's important to also note that 2 year survival rates after a heart transplant are similar, 75%-80% survival 2 years after a heart transplant.