3 ms·

Actually ibuprofen is a vasodilator unlike caffeine.

• ruined 5y ago
  caffeine is both a vasoconstrictor and a vasodilator, over the course of a dose. dilation is the second and longer-acting effect, and acclimation to that is what causes the withdrawal headaches. other vasodilators should help if the mechanism is different, to prevent continuing dependency.
• hunterb123 5y ago
  They're a very common combo used for pain and migraines though. Cannabis can be used for instant relief, but it opens your veins, causing headaches or worsening your migraine. Caffeine for extended headache relief. Sometimes you need an Advil and/or Aspirin depending on the pain. IANAD. Aspirin Acetaminophen and Caffeine or AAC is very effective.
  • shmel 5y ago
    I can totally see ibuprofen helping against headaches as it is a very common painkiller. I just pointed out that it works differently than caffeine.