>My question was what percentage of results in mice generalize to humans? Accuracy is very high when you are studying a metabolic pathway that is (near)identic

>My question was what percentage of results in mice generalize to humans? Accuracy is very high when you are studying a metabolic pathway that is (near)identical in humans and in mice. >To confirm I'm interpreting your answer directly. It depends on how the scientists use the tool. It is good at verifying certain aspects but not others. Yes. More precisely: animal models are accurate when the metabolic machinery in humans is also found in the animal model.