It's different from people to people, and from session to session. I've seen a variety of positive effects, but this is annecdotal, as they are reported by the

It's different from people to people, and from session to session. I've seen a variety of positive effects, but this is annecdotal, as they are reported by the people taking the substance themself. There is also the problem of long term vs short term. There are plenty of positive side effects that fade away after a few hours, days, or months. Often though, people report practical insights about oneself or life, that they could not get before, and those can be lasting. Some people report physical benefits as well. Paul Stamets famously said his speech impediment disapeared after a session. On a personnal level, what lasted for me were: - the understanding of some needs I had, and that I was not allowing myself to have. - the smoothing of autistic symptoms such. E.g: welcoming of physical contact. Both significantly improved my quality of life. I have to insist on the right conditions, though. There affect heavily both your immediate experience and the benefits you may get. If you intend to give it a try, get an experimented, serious and benevolent person to assist you. There are some groups that are specialized in the matter. I've done my first session with the psychedelic society: you pay them, and they organize a whole 3 days seminar for you. They were competent, caring, and amazingly benevolent. Unfortunatly they exist only in Europe.