Just to be clear, the title is incorrectly editorializing the article. Lots of people in this thread are correctly objecting to the unsupported overly-broad cla

Just to be clear, the title is incorrectly editorializing the article. Lots of people in this thread are correctly objecting to the unsupported overly-broad claim that there are no long-term effects. What the paper actually tested: > The trial is the first of its kind to thoroughly investigate the simultaneous administration of psilocybin. 89 healthy participants with no recent (within 1 year) use of psilocybin were recruited. 60 individuals were randomly picked to receive either a 10mg or 25mg dose of psilocybin in a controlled environment. In addition, all participants were provided with one-to-one support from trained psychotherapists. The remaining 29 participants acted as the control group and received a placebo, also with psychological support. > Participants were closely monitored for six to eight hours following administration of psilocybin and then followed up for 12 weeks. During this time, they were assessed for a number of possible changes, including sustained attention, memory, and planning, as well as their ability to process emotions. So the study did not find any deleterious effects in N=89, from _one_ dose, in a supportive environment, over a fairly short follow-up period. This not surprising to me and I'm not updating my model of the world in any way. This does _not_ prove that Psilocybin has no detrimental long-term effects. It just suggests that if they occur, they probably don't occur frequently enough to show up in the cursory glance that this study gave to the issue. Psilocybin is an exciting treatment for mental health issues; it's great that it's being destigmatized. It should be decriminalized, and it is much safer than alcohol and many other recreational drugs. However, like any drug, it has risks and can be misused. We need to be honest about the risks, understand that nothing is safe, and particularly, understand how to detect and respond to those risks when they do occur. edit: The title has now been changed, so this comment will read weirdly.