>separate antibody responses Of course not, they use the same mRNA. There's no reason to suspect they would in the first place. The difference in response in

>separate antibody responses Of course not, they use the same mRNA. There's no reason to suspect they would in the first place. The difference in response in the degree/intensity of response to the detected antigen. This is due to the concentration of mRNA in the vaccine (and therefore the concentration of antigen produced by the vaccine) Moderna creates a greater response than Pfizer due to concentration (100mcg vs 30mcg). I don't think there's a reason to believe that a moderna booster on top of a Pfizer initial vaccination would not increase the degree of response when an actual infection is detected. Immunology is not my field however so my knowledge is a bit limited.