BTW. I replaced every "let" and "contst" with "var" in your code, and it seems to run about 15% faster: https://jsfiddle.net/05xd1oft/ https://jsfiddle.net/05xd

BTW. I replaced every "let" and "contst" with "var" in your code, and it seems to run about 15% faster: https://jsfiddle.net/05xd1oft/ https://jsfiddle.net/05xd1oft/ Inserting the loop into a function really speeds it up in Chrome. Also, I have noticed, that for Float32Array, the rolled / unrolled performance is almost identical, but for Uint32Array, unrolled is about 30% faster: https://jsfiddle.net/aq06p94f/ https://jsfiddle.net/aq06p94f/