Since you called it out, and I live in Vancouver, BC - before the pandemic put a damper on travel I would say that Vancouver, BC and San Jose are pretty close -

Since you called it out, and I live in Vancouver, BC - before the pandemic put a damper on travel I would say that Vancouver, BC and San Jose are pretty close - not geographically but for virus transmission. More important than physical distance, for a virus, is how often and how many potential carriers move between the locations.