The only two opioids naturally found in the poppy that are also used in medicine are codeine and morphine. All others are semi-synthetic (chemical modifications

The only two opioids naturally found in the poppy that are also used in medicine are codeine and morphine. All others are semi-synthetic (chemical modifications of poppy alkaloids) or fully synthetic. Even most codeine is made by methylating morphine, since the poppy under-produces it relative to medical demand. https://en.wikipedia.org/wiki/Opioid#Semisynthetic_and_synthetic_opioids https://en.wikipedia.org/wiki/Opioid#Semisynthetic_and_synth...