3 ms·
Current variants are significantly more infectious (R0 used to be around 2.5-3.0 for the ancestral strain, Delta was 5+, Omicron estimates go up to 10). Vaccine
by pfg 5y ago
Current variants are significantly more infectious (R0 used to be around 2.5-3.0 for the ancestral strain, Delta was 5+, Omicron estimates go up to 10). Vaccine efficacy is also reduced for these variants. We've also scaled back non-pharmaceutical interventions in many places.
- krona 5y agoYou've neglected to account for the substantial difference in average hospital stay period between Delta and Omicron.
- pfg 5y agoDo we know how large this effect is for the unvaccinated? I'm still not sure if the numbers we're seeing from countries with relatively high seroprevalence through either vaccination, infection, or both can easily be applied to other countries. This UK report[1] does show a corrected Hazard Ratio of 0.76 relative to Delta, but more than half of this group seems to have had a previous infection. Not sure what it would look like if you exclude them. [1]: https://www.imperial.ac.uk/media/imperial-college/medicine/mrc-gida/2021-12-22-COVID19-Report-50.pdf https://www.imperial.ac.uk/media/imperial-college/medicine/m...