Not as far as I know. I doubt anyone would care about my hobby sites but my last work-place was used by thousands of businesses and we only used ipv4 on the lo

Not as far as I know. I doubt anyone would care about my hobby sites but my last work-place was used by thousands of businesses and we only used ipv4 on the load balancers and CDN endpoints. No issues, no customer complaints. AFAIK no customers asked for ipv6. If anything we had to support really old ciphers and had to make special firewalled API vips for customers that needed things like SSLv3 until they could get their vendors to upgrade their client libraries.