3 ms·
> although with a significant decrease in risk of catching or passing on the virus. With these effects waning on a time-scale similar to the first two doses. F
by nickysielicki 5y ago
> although with a significant decrease in risk of catching or passing on the virus. With these effects waning on a time-scale similar to the first two doses.
Food for thought: https://www.ucdavis.edu/health/covid-19/news/viral-loads-similar-between-vaccinated-and-unvaccinated-people https://www.ucdavis.edu/health/covid-19/news/viral-loads-sim...
Or the actual paper: https://www.medrxiv.org/content/10.1101/2021.09.28.21264262v1 https://www.medrxiv.org/content/10.1101/2021.09.28.21264262v...
The vaccine seems to result in less symptoms and makes your body clear the virus faster, but the evidence is coming in that peak viral load is not changed.
To me, this is the nightmare scenario of us going forward with emergency use authorizations. The whole theory behind the vaccine was that if your body was primed to handle the spike protein, you'd clear it faster and you'd feel better and critically: that you'd actually spread less virus because your body won't collect as much of it waiting for your immune system to react.
But only the first two parts of that ended up being true, because it appears that peak viral load isn't impacted. So now if you're vaaccinated, you feel fine so you don't test yourself and you don't isolate, but you're still spreading the virus as much as before, and r0 across the entire population is basically unchanged. It would almost be better for others if you weren't vaccinated, because you would have a lower chance of presenting asymptomatically and would be more likely to isolate.
The only silver lining is that it seems to clear faster, so the timespan where you're walking around with a high viral load (ie: superspreader) is smaller. But this isn't what they wanted.
- dangom 5y agoThis interpretation is misleading. There is no significant viral load difference between groups, but only looking at the subset of vaccinated people who actually got infected. Also, the study also suggests lower viral loads for the symptomatic population - regardless of vaccination, which is counterintuitive; and a higher ratio of vaccinated people developing symptoms (see counts in fig 1.). Also, the individual variability in viral load within each group is enormous, such that finding a "significant difference" would probably require many more participants than what the study recruited.