I am not a doctor but I did some research on this a couple of months ago. I recommend you carefully do your own research and talk to qualified doctors, but here

I am not a doctor but I did some research on this a couple of months ago. I recommend you carefully do your own research and talk to qualified doctors, but here is what I found: Psilocybin is for depression, trauma, PTSD, addiction, coping with pain, and generalized anxiety disorder. One dose induced rapid growth of dendritic spine size by 10% and density by 10% in the frontal cortex within 24 hours and lasted at least one month (they didn't monitor beyond that). Depression is associated with synaptic atrophy in the frontal cortex. Ketamine is for major depressive disorder, bipolar disorder, obsessive compulsive disorder, and social anxiety disorder.