3 ms·
> The 30 micrograms of ribonucleic acid in an mRNA vaccine dose get folded into protein and make their way into the lymph nodes in your armpit. They do not “sat
by mlyle 5y ago
> The 30 micrograms of ribonucleic acid in an mRNA vaccine dose get folded into protein and make their way into the lymph nodes in your armpit. They do not “saturate the body”.
I am pro-vaccine, but this isn't really true.
Note that we have animal studies that used luciferase mRNA to see where mRNA medications are transported and translated. There's some systemic transport no matter what, even with IM administration.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624045/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624045/
> Intravenous and intraperitoneal and to a lesser extent intramuscular and intratracheal deliveries led to trafficking of mRNA-LNPs systemically resulting in active translation of the mRNA in the liver for 1–4 days.
https://i.imgur.com/YSCFUQS.png https://i.imgur.com/YSCFUQS.png
Yes, the muscle in your arm does a lot of the production of the spike protein, and a lot of that spike protein is captured by the lymph nodes in your armpit. But decent chunk of the mRNA goes to your liver, too, and a big amount of spike protein circulates systemically no matter where it's produced.