4 ms·

And 4 doses for the coming Sigma variant? It seems never ending with these leaky vaccines

mlyle 5y ago
> And 4 doses for the coming Sigma variant? It seems never ending with these leaky vaccines On the other hand, these "leaky vaccines" have already prevented a massive amount of mortality. Yes, the duration and quality of protection, even boosted, against Omicron is unfortunate... but even 2 doses can still be expected to save a high number of lives from Omicron.
- chana_masala 5y ago
  I doubt that in the long term. The long term health effects of the vaccine are largely unknown but already looking grim.
  - jbd28 5y ago
    - chana_masala 5y ago
      - dang 5y ago
        Could you please stop posting flamewar comments to HN? You've been doing it a lot, unfortunately, and we ban that sort of account. It's not what this site is for, and it destroys what it is for. https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
        chana_masala 5y ago
        OK, thank you
    - chana_masala 5y ago
      > no vaccine has ever caused a side effect after 9 weeks post administration in the history of modern medicine. I can't believe this is your actual position. It's so wild I have to believe you're trolling. Even Paul Offit would agree.
    - dang 5y ago
      Please do not post in the flamewar style to HN. We're trying to avoid that here. Your comment would be fine with just the second sentence. https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
  - jacquesm 5y ago
    > The long term health effects of the vaccine are largely unknown but already looking grim This is not supported by any evidence.
    - chana_masala 5y ago
- headsoup 5y ago
  Not longer term if they end up creating hotter variants through vaccine escape. Look into OAS, I think it's a good thing the latest variant came from Africa and not Israel
  - chana_masala 5y ago
    Great point regarding Africa vs hypervaccinated Israel. However I am unfamiliar with what you mean by OAS.
    - headsoup 5y ago
      Original Antigenic Sin. See here: https://pubmed.ncbi.nlm.nih.gov/28479213/ https://pubmed.ncbi.nlm.nih.gov/28479213/ Here's also some analysis about this effect with Omicron, which seems honest about the limitations: https://boriquagato.substack.com/p/theres-something-antigenic-in-denmark https://boriquagato.substack.com/p/theres-something-antigeni...
      - chana_masala 5y ago
        Ah great, thank you for sharing!
jbd28 5y ago
Wait until you see how many doses people need for tetanus, pertussis, and diphtheria (4 in 18 months with boosters every decade)
- chana_masala 5y ago
  Wait until you see how bad the pertussis vaccine is at protecting against whooping cough! Are you up to date on your boosters for DPT? I don't know anyone who has maintained that.

> And 4 doses for the coming Sigma variant? It seems never ending with these leaky vaccines On the other hand, these "leaky vaccines" have already prevented a massive amount of mortality. Yes, the duration and quality of protection, even boosted, against Omicron is unfortunate... but even 2 doses can still be expected to save a high number of lives from Omicron.

chana_masala 5y ago
I doubt that in the long term. The long term health effects of the vaccine are largely unknown but already looking grim.
- jbd28 5y ago
  - chana_masala 5y ago
    - dang 5y ago
      Could you please stop posting flamewar comments to HN? You've been doing it a lot, unfortunately, and we ban that sort of account. It's not what this site is for, and it destroys what it is for. https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
      - chana_masala 5y ago
        OK, thank you
  - chana_masala 5y ago
    > no vaccine has ever caused a side effect after 9 weeks post administration in the history of modern medicine. I can't believe this is your actual position. It's so wild I have to believe you're trolling. Even Paul Offit would agree.
  - dang 5y ago
    Please do not post in the flamewar style to HN. We're trying to avoid that here. Your comment would be fine with just the second sentence. https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
- jacquesm 5y ago
  > The long term health effects of the vaccine are largely unknown but already looking grim This is not supported by any evidence.
  - chana_masala 5y ago
headsoup 5y ago
Not longer term if they end up creating hotter variants through vaccine escape. Look into OAS, I think it's a good thing the latest variant came from Africa and not Israel
- chana_masala 5y ago
  Great point regarding Africa vs hypervaccinated Israel. However I am unfamiliar with what you mean by OAS.
  - headsoup 5y ago
    Original Antigenic Sin. See here: https://pubmed.ncbi.nlm.nih.gov/28479213/ https://pubmed.ncbi.nlm.nih.gov/28479213/ Here's also some analysis about this effect with Omicron, which seems honest about the limitations: https://boriquagato.substack.com/p/theres-something-antigenic-in-denmark https://boriquagato.substack.com/p/theres-something-antigeni...
    - chana_masala 5y ago
      Ah great, thank you for sharing!

jbd28 5y ago

Wait until you see how many doses people need for tetanus, pertussis, and diphtheria (4 in 18 months with boosters every decade)

chana_masala 5y ago
Wait until you see how bad the pertussis vaccine is at protecting against whooping cough! Are you up to date on your boosters for DPT? I don't know anyone who has maintained that.