You can absolutely use VR for more than short periods quite comfortably without getting fatigue and eyestrain, assuming you're not running at a low FPS and your

You can absolutely use VR for more than short periods quite comfortably without getting fatigue and eyestrain, assuming you're not running at a low FPS and your tracking is accurate. I often use it for programming, and I'm able to stay quite comfortable for around twelve hours at a stretch multiple times a week. I also play some reasonably competitive, fast-paced games, and there's no discomfort from playing those at long intervals, either.