4 ms·
Low antibodies != low immune response
by tchalla 5y ago
Low antibodies != low immune response
- ubercore 5y agoThe way I read this paper is that they're talking specifically about neutralization, not just antibody response.
- chana_masala 5y agoI recall hearing that as well but I can't quite remember what the rest of the picture is - something about the other parts of the immune system being able to do the needed work? Or that it was shown that someone with zero antibodies could still be immune?
- F30 5y agoOther parts of the immune system, specifically T-cell response. The simplified bottom line is that antibodies provide a quick response that also prevents many cases of mild disease. T-cell immunity lasts longer, appears more universal against variants and should still work relatively well against severe cases.
- tchalla 5y agoBasically, memory B-cells remember the code for anti-bodies and they are produced "on demand". Please see the graph in the figure below. https://askabiologist.asu.edu/memory-b-cell https://askabiologist.asu.edu/memory-b-cell