Personally, Django. I know it so I can develop relatively quickly with it plus it has so much built in already. It's also a mature framework so chances of run

Personally, Django. I know it so I can develop relatively quickly with it plus it has so much built in already. It's also a mature framework so chances of running into bugs for normal tasks is lower than newer/cutting edge and if I do need help there are high chances that someone else has already dealt with it. Deployment and scaling can also be taken care of by something like Heroku which already supports Django so I can best use my time focusing on the development of valuable business logic rather than reinventing the wheel and maintenance.