Since you mentioned React Native, I assume you're pointing towards mobile app development. The best stack combination for me has been webview + PWA + webassembl

Since you mentioned React Native, I assume you're pointing towards mobile app development. The best stack combination for me has been webview + PWA + webassembly + toucaan to create an intrinsically designed universal mobile-web app. There's something really powerful about deploying just one application on three separate distribution platforms. And it's not even a monorepo anymore!