I think my problem with the AlphaFold narrative is that it's being treated as if it's something new, or that (as I see frequently) "protein folding is solved".

I think my problem with the AlphaFold narrative is that it's being treated as if it's something new, or that (as I see frequently) "protein folding is solved". As far as I can tell, our knowledge of protein folding hasn't increased at all. It's a black box of homology modeling and its standing on the shoulders of decades of fundamental wet bench biochemistry and simple wouldn't be possible without it. Google came along and tweaked something to make it significantly better, but still not good enough.