4 ms·
A minor point in here corrected a misconception I didn't realize I held: > T-cell mechanisms are also crucial, and T-cell data are much harder to come by. Sinc
by kevinmchugh 5y ago
A minor point in here corrected a misconception I didn't realize I held:
> T-cell mechanisms are also crucial, and T-cell data are much harder to come by. Since you don't see the number of papers in that area as you do for antibody profiling, it easy to think that they don't matter as much, but that's not true.
- ethbr0 5y agoI'd be really interested to hear someone in microbiology opine on the difficulties in measuring T-cell and other non-antibody data? What makes it so much harder?
- VeninVidiaVicii 5y agoYou're probably looking for an immunologist.
- rossdavidh 5y agoNot the expert you're looking for, but I recall a past Derek Lowe article mentioned in passing that it was much more labor-intensive (presumably by a trained lab tech) to get T-cell data. Again, this is just my memory of a past Derek Lowe article, which I might be misremembering.
- KaiserPro 5y agoThere are mechanisms for t-cell testing in reasonably wide use now. from what I understand its not done that much comparatively is because its bloody expensive. I think one of the mechanisms is here: https://en.wikipedia.org/wiki/ELISpothttps://en.wikipedia.org/wiki/ELISpot https://en.wikipedia.org/wiki/ELISpothttps://en.wikipedia.or... However I would take all of this with a pinch of salt. I asked my doctor friend about it, they said "We use t-cell tests for a bunch of things, but its really expensive. I can't remember what thing we were looking for, probably TB, everyone had TB in that ward, so it might be that."