Yes, my intention with the question was that Remix seems to be saying we have some special optimizations that make this edge-native, which I interpreted to mean

Yes, my intention with the question was that Remix seems to be saying we have some special optimizations that make this edge-native, which I interpreted to mean, we make React work magically better on the edge. There has always been a problem with taking front-end code and making it talk to the backend, and when you add a new backend like workers (and start storing data inside CloudFlare KV, etc) then it suddenly looks more and more complicated. After reading about Remix, it seems like they are suggesting they make it so your React hooks have some special logic that makes them work with edge compute more seamlessly. I know SvelteKit is thinking about the same kind of thing (with SSR, for example) and loader functions but I don't know enough about either to compare them.