What would a low capital biological research institute look like? Like nothing?....because it can't exist? (This is the answer in my experience). I ask only to

What would a low capital biological research institute look like? Like nothing?....because it can't exist? (This is the answer in my experience). I ask only to see if anyone has any ideas. The consensus seems to be that you will always need 100s of millions of dollars to do something like this.