3 ms·
So you are saying that one way to solve a problem quick is to create a pandemic around it ... hmm I think the most important takeaway from the pandemic is that
by cblconfederate 5y ago
So you are saying that one way to solve a problem quick is to create a pandemic around it ... hmm
I think the most important takeaway from the pandemic is that accelerated phase 2/3 trials will become the norm
- onychomys 5y agoIt should probably be noted here that for the mRNA vaccines, the only reason that the trials seemed accelerated is that they were able to find so many infected participants, and so were able to reach their stated endpoints more quickly.
- xiphias2 5y agoI’m not so sure about that. People worked all day and night and through weekends, were much more flexible with streaming data instead of getting it in one big package after it all arrived. I’m extremely thankful for all people who took part in letting me seeing my parents again without masks.
- ksd482 5y agoI don’t think that’s what he/she is saying. How did you infer that? What he’s/she’s saying is how to make the best out of a crisis after the fact.
- vlovich123 5y agoMy understanding is that the only reason this worked for mRNA is that it was basically already at the end point of the development cycle of figuring out which disease to apply it to. It was just waiting for patients to demonstrate efficacy and safety. COVID-19 provided that opportunity. This is not a repeatable model for other new technologies though. Now that mRNA safety has been proven out, the hurdles to applying it to other things are drastically reduced (as they would have been once the first mRNA drug got approved). Similarly, having a ready population pool and an urgent need is not likely to come up again although maybe mRNA drugs in general have a safety profile that might warrant giving them to patients who have no other alternative.