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„the flu vaccine“? Which one?

• s1artibartfast 5y ago
  The first vaccines in 1933 were against A type influenzas, followed by vaccines against against B type influenzas in 1942. Here is a pretty good summary of the history of vaccine development. https://www.medscape.com/viewarticle/812621_1 https://www.medscape.com/viewarticle/812621_1 While nearly all influenza vaccines generate similar antibodies, Covid and influenza vaccines generate significantly different antibodies Influenza vaccines generate antibodies against influenza Hemagglutinin proteins targeting sialic acid receptors Covid vaccines generate antibodies for (S) glycoproteins targeting ACE-2 receptors. In short, we have 80+ years of experience generating antibodies for hemagglutinin, and much less for (S) glycoproteins. https://en.wikipedia.org/wiki/Coronavirus_spike_protein https://en.wikipedia.org/wiki/Coronavirus_spike_protein https://en.wikipedia.org/wiki/Hemagglutinin_(influenza) https://en.wikipedia.org/wiki/Hemagglutinin_(influenza)