3 ms·
Here's the paper: https://www.nature.com/articles/s43587-021-00151-2 https://www.nature.com/articles/s43587-021-00151-2
by hirenj 5y ago
Here's the paper:
https://www.nature.com/articles/s43587-021-00151-2 https://www.nature.com/articles/s43587-021-00151-2
- deleted 5y ago[deleted]
- hirenj 5y agoIt's an odd protein they're hitting - GPMNB is expressed pretty widely, so I wonder what the proteoform is that they're targeting/recognising here. Can't get to the paper using all the usual tricks, so it's hard to say what exactly they're immunising with, which could answer a lot of my questions.
- narrator 5y agoGPMNB seems to be expressed in cancer cells. Cancer cells are usually kind of screwed up and senescent. Maybe it's one of those little anti-cancer Rube Goldberg machines like p53 that starts popping off triggering apoptosis when things get weird in the cell.