3 ms·

This is a significant and life changing side effect. One that should be getting more coverage than it is. Additionally there appears to be no followup with indi

This is a significant and life changing side effect. One that should be getting more coverage than it is. Additionally there appears to be no followup with individuals in the at risk categories post vaccination.

spullara 5y ago
Huh. I got a survey every day for weeks and then once a week for a few months. (In the US)
nerdponx 5y ago
What are the at-risk categories for GBS? Are the categories different for mRNA vaccines vs. viral-vector vaccines vs. other kinds of vaccines?
- neogodless 5y ago
  In the linked paper, it describes the most common ages/genders, and also specifies that there was no increase in GBS incidence for recipients of mRNA vaccines. This is specific to the J&J vaccine.
jeroenhd 5y ago
I think it should receive quite a lot of coverage, but not until it's been peer reviewed. I can write a whole paper about how the vaccine turns your skin magnetic and upload it to medRxiv, but that doesn't mean much. Many of the most worrying news stories about the vaccines have been either disproven or taken out of proportion because of early drafts like these. We'll have to be patient for a bit longer before we can draw any conclusions from this paper. As their homepage says: > Caution: Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
- mrjangles 5y ago
  You don't know what peer review is. >I can write a whole paper about how the vaccine turns your skin magnetic and upload it to medRxiv, but that doesn't mean much. Yes you could, and, provided you wrote it in such a way that people didn't think it was a joke, you would get published in Nature for sure. Only later when people try to reproduce your work would they realize you are a fraud, and depending on what country you work in, different disciplinary action might be taken (though probably not).
  - alexvoda 5y ago
    While true that reproducibility is the truly useful filter, peer review is still a valid pre-filter. Do you believe peer review suffers from both false positives and false negatives (type I and II errors, don't remember which is which)? As a side note, we need better terminology than type I and II or false positive/negative. Type I and II is completely opaque to meaning. False positive and negative is unclear because sometimes the negative is desirable and othertimes the positive is desirable. Maybe RDO and AUO: rejected desirable option and accepted undesirable option.

spullara 5y ago

Huh. I got a survey every day for weeks and then once a week for a few months. (In the US)

nerdponx 5y ago

What are the at-risk categories for GBS? Are the categories different for mRNA vaccines vs. viral-vector vaccines vs. other kinds of vaccines?

neogodless 5y ago
In the linked paper, it describes the most common ages/genders, and also specifies that there was no increase in GBS incidence for recipients of mRNA vaccines. This is specific to the J&J vaccine.

jeroenhd 5y ago

I think it should receive quite a lot of coverage, but not until it's been peer reviewed. I can write a whole paper about how the vaccine turns your skin magnetic and upload it to medRxiv, but that doesn't mean much. Many of the most worrying news stories about the vaccines have been either disproven or taken out of proportion because of early drafts like these. We'll have to be patient for a bit longer before we can draw any conclusions from this paper. As their homepage says: > Caution: Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

mrjangles 5y ago
You don't know what peer review is. >I can write a whole paper about how the vaccine turns your skin magnetic and upload it to medRxiv, but that doesn't mean much. Yes you could, and, provided you wrote it in such a way that people didn't think it was a joke, you would get published in Nature for sure. Only later when people try to reproduce your work would they realize you are a fraud, and depending on what country you work in, different disciplinary action might be taken (though probably not).
- alexvoda 5y ago
  While true that reproducibility is the truly useful filter, peer review is still a valid pre-filter. Do you believe peer review suffers from both false positives and false negatives (type I and II errors, don't remember which is which)? As a side note, we need better terminology than type I and II or false positive/negative. Type I and II is completely opaque to meaning. False positive and negative is unclear because sometimes the negative is desirable and othertimes the positive is desirable. Maybe RDO and AUO: rejected desirable option and accepted undesirable option.