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This paper from Africa Health Research Institute shows a 41x reduction in effectiveness of pfizer vaccine for omicron. https://www.ahri.org/omicron-incompletel
by millettjon 5y ago
This paper from Africa Health Research Institute shows a 41x reduction in effectiveness of pfizer vaccine for omicron.
https://www.ahri.org/omicron-incompletely-escapes-immunity-induced-by-the-pfizer-vaccine/ https://www.ahri.org/omicron-incompletely-escapes-immunity-i...
https://www.ahri.org/wp-content/uploads/2021/12/MEDRXIV-2021-267417v1-Sigal.pdf https://www.ahri.org/wp-content/uploads/2021/12/MEDRXIV-2021...
- Brybry 5y agoThis preprint also shows reduced antibody neutralization of omicron in comparison to delta (including for double vaccinated + previous infection). Note the sample sizes for all these studies is small. 12 participants for the AHRI paper and 8 to 20 per group for this one. https://www.medrxiv.org/content/10.1101/2021.12.07.21267432v1.full.pdf https://www.medrxiv.org/content/10.1101/2021.12.07.21267432v...
- swader999 5y agoSample size doesn't really matter much in this kind of study.
- peteradio 5y agoIdeally you'd match it to some population of interest. For my own medical affairs, I don't care what grand-pappy's results are here, I want to know how cousin Tim fairs.
- Stanleyc23 5y agoWhy not? I’m no statistician, so my basic understanding is you should always prefer bigger sample sizes to ensure statistically significant findings.
- fsh 5y agoThis paper doesn't even attempt to measure effectiveness. It measures neutralization titers which is a totally different thing.