2 ms·
From reading around (not a biologist), I get the impression that there's some kind of super-linear immunity building, not just waning protection. Standard child
by rich_sasha 5y ago
From reading around (not a biologist), I get the impression that there's some kind of super-linear immunity building, not just waning protection. Standard children's vaccines often have a few doses, and not evenly spaced.
Soo... you're building up better immunity against the "baseline" virus with each dose. That immunity translates to some (reduced) immunity to the variants. But if the "baseline" is high enough, you can afford some drop in efficiency.
Perhaps in some ideal world, the boosters would be tuned to the variants. But as you say, they would need to be re-tested etc. Cf. the AZ vaccine, which through some arcane process causes (extremely rare) blood clots, it's probably hard to verify ahead of time a modified vaccine wouldn't suffer from such side effects.
- lordlimecat 5y agoMy understanding is that there is poor evidence that any of the vaccines cause a statistically significant increase in blood clots over any other vaccine-- that the act of getting an immunization can (very rarely) trigger a blood clot regardless of what it is and COVID just happens to be in the hyper-sensitive spotlight.
- m0llusk 5y agoIt is likely that the cause or at least a cause of rare blood clots has been found. There is a chance that adenovirus used to make vaccines can bind to a specific clotting factor in the blood which then in rare cases may be attacked by antibodies created by the immune system to fight the infection. https://www.biospace.com/article/researchers-find-possible-cause-of-rare-clotting-side-effect-in-astrazeneca-covid-19-vaccine/ https://www.biospace.com/article/researchers-find-possible-c...