For self-hosting one instance, there's little difference. What matters more is how well the tooling you use with with your DB supports it. Recently I've been o

For self-hosting one instance, there's little difference. What matters more is how well the tooling you use with with your DB supports it. Recently I've been on a .NET 6.0 project and the Entity Framecore Core MySQL provider was broken for what I was doing. The one for Postgres worked fine so we chose that. >My only experience with postgres is running a brew update and it completely borking the database and having to track down some cryptic post in order to fix it. I find containers work wonders for databases, whether it is for using specific versions, segregating instances, keeping your system clean etc. I keep at least one of MySQL, Mango, MSSQL and Postgres running at all times. I would never install one natively.