4 ms·

Fecal transplants also have put people in remission.

by vimy 5y ago

GhettoComputers 5y ago
This isn’t a panacea unfortunately, this caused a woman with an infection to eliminate it, but caused her to become obese. https://www.iflscience.com/health-and-medicine/woman-becomes-obese-after-fecal-transplant-overweight-donor/ https://www.iflscience.com/health-and-medicine/woman-becomes... > At the time, the woman was a healthy 136 pounds with a normal BMI of 26. Her daughter weighed 140 pounds at the time, with a BMI of 26.6, but became overweight shortly afterward. Following the therapy, the woman’s symptoms vanished and she no longer experienced recurrent infections. >Sixteen months later, however, the woman reported unintentional weight gain of 34 pounds and met the criteria for obesity. Two and a half years after the transplant, the woman weighed 177 pounds with a BMI of 34.5, despite a medically supervised liquid protein diet and exercise program.
- m0lecules 5y ago
  I would bet money that the donor was obese. Ah, yes indeed, you failed to include the headline from the article: "Woman Becomes Obese After Fecal Transplant From Overweight Donor"
  - GhettoComputers 5y ago
    Did you read my post? > At the time, the woman was a healthy 136 pounds with a normal BMI of 26. Her daughter weighed 140 pounds at the time, with a BMI of 26.6, but became overweight shortly afterward. Following the therapy, the woman’s symptoms vanished and she no longer experienced recurrent infections. >Sixteen months later, however, the woman reported unintentional weight gain of 34 pounds and met the criteria for obesity. Two and a half years after the transplant, the woman weighed 177 pounds with a BMI of 34.5, despite a medically supervised liquid protein diet and exercise program.
- rendang 5y ago
  That anecdote would not cause me to think less of fecal transplants, but quite the opposite. If there is a causative lever in the microbiome that can affect obesity, one could apply that in reverse, so that if you had the right source, the donor from that story could reduce their weight by receiving a transplant themselves.
  - GhettoComputers 5y ago
    I think it’s useful to be selective, you have to have similar biomes, you can’t just use anyone’s feces, it’s why her daughter’s was used. I said it’s not a panacea but it is a good area to research.

Fecal transplants also have put people in remission.

by vimy 5y ago

Fecal transplants also have put people in remission.

This isn’t a panacea unfortunately, this caused a woman with an infection to eliminate it, but caused her to become obese. https://www.iflscience.com/health-and-medicine/woman-becomes-obese-after-fecal-transplant-overweight-donor/ https://www.iflscience.com/health-and-medicine/woman-becomes... > At the time, the woman was a healthy 136 pounds with a normal BMI of 26. Her daughter weighed 140 pounds at the time, with a BMI of 26.6, but became overweight shortly afterward. Following the therapy, the woman’s symptoms vanished and she no longer experienced recurrent infections. >Sixteen months later, however, the woman reported unintentional weight gain of 34 pounds and met the criteria for obesity. Two and a half years after the transplant, the woman weighed 177 pounds with a BMI of 34.5, despite a medically supervised liquid protein diet and exercise program.

m0lecules 5y ago
I would bet money that the donor was obese. Ah, yes indeed, you failed to include the headline from the article: "Woman Becomes Obese After Fecal Transplant From Overweight Donor"
- GhettoComputers 5y ago
  Did you read my post? > At the time, the woman was a healthy 136 pounds with a normal BMI of 26. Her daughter weighed 140 pounds at the time, with a BMI of 26.6, but became overweight shortly afterward. Following the therapy, the woman’s symptoms vanished and she no longer experienced recurrent infections. >Sixteen months later, however, the woman reported unintentional weight gain of 34 pounds and met the criteria for obesity. Two and a half years after the transplant, the woman weighed 177 pounds with a BMI of 34.5, despite a medically supervised liquid protein diet and exercise program.
rendang 5y ago
That anecdote would not cause me to think less of fecal transplants, but quite the opposite. If there is a causative lever in the microbiome that can affect obesity, one could apply that in reverse, so that if you had the right source, the donor from that story could reduce their weight by receiving a transplant themselves.
- GhettoComputers 5y ago
  I think it’s useful to be selective, you have to have similar biomes, you can’t just use anyone’s feces, it’s why her daughter’s was used. I said it’s not a panacea but it is a good area to research.