4 ms·

I wonder if anyone has tried a treatment with a non-refrigerated diet EDIT: I read some more and found “Nutritional treatment of CD was first proposed by Voitk

• uniqueuid 5y ago
  Right, this is what the authors demand: "as no single experiment can definitively confirm the theory, we must continue to test it with additional works. Among them [and even if insufficient to definitively validate the hypothesis], a randomised clinical trial comparing patients with low versus high exposure to Yersinia would be an important step."
• teruakohatu 5y ago
  Essentially they found that tube fed diets do help, and they are effectively refrigeration free. > "Furthermore, no specific foodstuff has been incriminated in CD, and combining enteral nutrition with a highly controlled oral diet was recently shown to be effective" ... "It should be noted, however, that enteral nutrition effectively excludes refrigerated foods." They go on to say that enteral nutrition differ from regular diets so that the mechanism that make them work may not to the fact that they are unrefrigerated. A refrigeration free diet would not be impossible today, but hard. Given he prevalence of this bacteria today, non-electric cold stores would probably also need to be removed from the supply chain, making even a pre-industrial Western diet problematic. A sufficiently cooked vegan diet, minus everything that causes problems with people that suffer from Crohn's Disease, maybe would work? Ideally with vegetables that have not been refrigerated. Winter would be pretty bleak.
  • rini17 5y ago
    Pre-industrial western diet cold stored food was either salted (meat), fermented (cabbage, cheese) or alive (fruit, root vegetables, potatoes)...so, it's possible there was completely different microbiology than in modern processed food.
  • ampdepolymerase 5y ago
    If tube fed diets are the trick, why not just go with Soylent? It's about as bacteria-free as food can reasonably get.
    • bladegash 5y ago
      For many with Crohn’s, this is more or less the treatment. Many times it is less because it’s most effective, and more because surgeries removing portions of the large/small intestines has made them incapable of digesting other forms of food. I guess my question would be - would you want to live on Soylent the rest of your life, if it could be avoided? I think most would answer no.
    • atdrummond 5y ago
      Better off getting a proper elemental diet. Plenty of things in soylent that can set me off if I’m already flaring or predisposed to one.
      • jcrben 5y ago
        IIRC studies have generally shown that elemental and polymeric formulas are similarly effective, but I agree that Soylent has some strange stuff that prolly wouldn't agree with me. I had a good experience with Ensure Plus (chocolate) which was used in a clinical trial or two in Australia (or maybe New Zealand). But I used the one without fiber whereas the one with fiber bothered me.
        • xeromal 5y ago
          Ensure has been a godsend for me too particularly during Ramadan. lol. A great way to get some wholesome calories when needed.