> Everything affects everything else, and the correct questions to ask are how much? I wish this kind of statement would be applied to biology, indeed there is

> Everything affects everything else, and the correct questions to ask are how much? I wish this kind of statement would be applied to biology, indeed there is system biology, but it does not seems to be used widely. I read avidly everything which is published in neurodegenerative diseases. Most of academic publications claim that one or another of ten of thousands molecules have a positive influence on these diseases. Clearly the biotech or pharmaceutical industries does not trust most of these publications as little of these suggestions are translated in clinical trials. I do not want to say that the biotech/pharma industries are more rational either as it happens that: - They seems to apply one molecule to multiple unrelated diseases until they find a suitable target (which more than often they do not find) - They apply repetitively the same molecule to the same disease even when clinical trials show it is not effective (for example memantine and ALS).