chronically-elevated blood sugar is quite probably the #1 cause of vascular problems (heck, it's highest association is with hypertension, these go hand in hand

chronically-elevated blood sugar is quite probably the #1 cause of vascular problems (heck, it's highest association is with hypertension, these go hand in hand), hypertension is itself often associated with a common magnesium deficiency (stiffness is what happens when magnesium is insufficient and calcium is overexpressed, I mean this is the basic role of magnesium in the cell, "relaxing" the contraction brought on by calcium), this is schematic and a layman view but I believe basically correct