> The MRNAs are non-sterilizing The vaccines we have are non-sterilizing - and my understanding is that the reason is mostly because we needed at least somethi

> The MRNAs are non-sterilizing The vaccines we have are non-sterilizing - and my understanding is that the reason is mostly because we needed at least something very quickly and sterilizing vaccines for respiratory virus are harder to research. It is not inherent property of the technology as far as I know. Sterilizing vaccines for COVID seem to be theoretically possible. "Natural" infection generates stronger immune response on mucus membranes as well as deep inside the body and that provides higher protection against infection. There's no reason why that wouldn't be possible to replicate using a vaccine. But nobody succeeded at making one yet, so we'll have to see if it's practical.