3 ms·
The link references a specific response to remdesivir, but I don't see how the selective pressure isn't the same in the broader case of low-level or asymptomati
by adamiscool8 5y ago
The link references a specific response to remdesivir, but I don't see how the selective pressure isn't the same in the broader case of low-level or asymptomatic illness persisting in a vaccinated person, particularly when they'll be mingling more and taking less precautions.
- angelzen 5y agoA paper, while not specifically addressing vaccination in immunocompromised patients, documents pretty clearly the phenomenon of runaway mutation chains in such patients. https://www.nejm.org/doi/full/10.1056/NEJMsb2104756 https://www.nejm.org/doi/full/10.1056/NEJMsb2104756 Edit: Another piece, specifically addressing immunocompromised + covid + vaccines: "Studies have shown that immunocompromised people are more vulnerable to being hospitalized or dying from COVID and less likely to develop strong protection from vaccination. But there are also some hopeful signs: additional doses of some COVID vaccines, strategic timing of immunosuppressive treatments and prophylactic COVID treatments may boost protection among some immunocompromised individuals—and restore at least some of the freedoms they have lost." https://www.scientificamerican.com/article/how-immunocompromised-people-without-strong-vaccine-protection-are-coping-with-covid/ https://www.scientificamerican.com/article/how-immunocomprom...