A couple more studies related to the findings in the OP: https://www.statnews.com/2021/10/11/mouse-experiments-with-old-drug-suggest-new-approach-to-alzheimers

A couple more studies related to the findings in the OP: https://www.statnews.com/2021/10/11/mouse-experiments-with-old-drug-suggest-new-approach-to-alzheimers-treatment/ https://www.statnews.com/2021/10/11/mouse-experiments-with-o... https://www.nia.nih.gov/news/study-reveals-how-apoe4-gene-may-increase-risk-dementia https://www.nia.nih.gov/news/study-reveals-how-apoe4-gene-ma... It's also very suggestive that Vitamin D deficiency is associated with reduced choline metabolism in the brain: https://pubmed.ncbi.nlm.nih.gov/3753932/ https://pubmed.ncbi.nlm.nih.gov/3753932/