3 ms·
So what is, or are, the "small-molecule inhibitors"? (I don't have access to the full texts of the papers.) Also, what makes them confident these inhibitors "s
by fernly 5y ago
So what is, or are, the "small-molecule inhibitors"? (I don't have access to the full texts of the papers.)
Also, what makes them confident these inhibitors "suppress breast cancer progression and metastasis"? Does this mean only in the mouse model? Because the original article says "will be ready for human trials in a few years".
- tux3 5y agoA small molecule is exactly what it says on the tin: small compounds. Small enough that they can pass through cell membranes. Inhibitors block some biological pathway, which in general could be any number of things. In this case the drug blocks a specific protein that we believe cancer cells specifically need, meaning the cancer cells might fail faster than the rest of your body if we inhibit it.