It's really very much like lego: the virus is a three-dimensional shape that fits certain elements on cells where it docks and enters. Antibodies are also shape

It's really very much like lego: the virus is a three-dimensional shape that fits certain elements on cells where it docks and enters. Antibodies are also shaped to to fit into some spot on the virus' surface. When the virus evolves, it changes its shape and, due to evolution, these changes tend to be in its favor. Practically, it probably means a loss of about 3-4 months, i. e. the winter will be more like last year's than we might have hoped. Your vaccination is almost certain to still be effective in saving your life, but infection and retransmission could move from an exception to a rather common event. I'd expect an update to the vaccines becoming more urgent now, and with all the resources that have been directed at the first round of that effort, the process will be quite fast, especially in the manufacturing stage. So: new vaccine around February/March, but rollout to everyone in the rich countries within 6-12 weeks this time around.