Mutagenesis will continue as long as there are viruses making more viruses. If I had to guess our future, COVID will become endemic but with less potency. We w

Mutagenesis will continue as long as there are viruses making more viruses. If I had to guess our future, COVID will become endemic but with less potency. We will manage it with vaccines and anti-virals. Lockdowns and restrictions? Frankly, I don't think business will allow it, particularly given how hard it is to demonstrate their efficacy (we can't look at the parallel universe where restrictions weren't imposed by a nation).